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Former war hero Cameron Poe (Nicolas Cage) is sentenced to eight years in prison when he accidentally kills a man in a barroom brawl while defending his pregnant wife. When his release comes through, he's eager to see the daughter he's never met. However, Poe's original flight is delayed, so he's put aboard a flight transporting ten of the most dangerous men in the American penal system to a new high-security facility. One of the criminals, Cyrus "The Virus" Grissom (John Malkovich), is a serial killer and insane genius who ...

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